Cleanance Comedomed is particularly indicated for acne-prone skin with spots and blackheads. Teenagers from 12 years old, adults Cleanance Comedomed offers a light texture, quickly absorbed as soon as it is applied, leaving the skin refreshed and mat. Pleasant and practical, with its pump bottle, just one press provides the right dose of product. Can be used alone or in combination with a local medicinal treatment (excluding oral isotretinoin). Apply to entire face twice a day. Good make-up base. Key Components 67.5% Avène Thermal Spring Water soothes and hydrates the skin, hence keeping it balanced. 25% Comedoclastin, a patented active ingredient which helps to regulate sebum production. Indication Acne-prone skin How to use Apply Avène Cleanance Comedomed in the morning and evening onto clean skin, being careful to avoid the eye contour.